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2024 CPHI Exhibition Chinese Official Website Invitation Poster

Product Category

ChiRial focuses on biosynthetic chiral compound materials and has 7 product lines

Pharmaceutical Intermediates
Health Care Ingredient
Non-natural Amino Acid
Cosmetic Ingredient
Herbal Extract
Biological Material
coenzyme

Application scenarios

ChiRial uses biosynthesis to create value and achieve a healthy and beautiful future for human beings

Key Technology

The engine of ChiRial's development and the guarantee of high-quality product supply for our customers

Computation Analysis and Directed Evolution of Enzymes

ChiRial has accumulated more than 500 leading enzymes. With the rapid development of science and technology, we have access to an increasing amount of useful information, knowledge and resources. The multidisciplinary background of ChiRial’s R&D team allows us to develop a range of high-quality and excellent enzymes using our expertise and skills in computational science, biology and pharmaceutical chemistry. Through functional analysis of potential target molecules, genetic modification using molecular biology techniques, followed by screening and optimization of target enzyme molecules, ChiRial has developed a library of leading enzymes that can effectively synthesize chiral materials. In the future, ChiRial will develop more effective bio-catalytic tools basing on this foundation.

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Fermentation Engineering

ChiRial has a variety of biological expression systems. In addition to using computational science and genetic engineering for targeted screening and modification, ChiRial has optimized the biological expression systems, which including E.coli, Yeast and other eukaryotic cells. Based on these expression systems, ChiRial team are able to perform batch fermentation according to the needs of product development.

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Green Chiral Bio-Chem

ChiRial focuses on the development and production of chiral materials. The phenomenon 'mirror-image, non-superimposable molecules' is called chirality. Just like our right hand mirrors our left but will never fit comfortably into a left-handed glove. Essential biomolecules of life, like amino acids and sugars, are chiral. Though they exist in mirror symmetrical pairs named enantiomers, the modern life selectively uses only one of the enantiomers, such as DNA have its right-handed double helix and amino acids in proteins only of the left-handed variety. Therefore, ChiRial believe it is essential to use the correct materials for our health.

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Polymerization and Performance Characterization of Biomaterials

Various materials meet different customer needs. As a pioneer in the reverse synthesis of PHA materials, ChiRial has an a library of chiral compound monomers for PHA materials, and has also developed controllable polymerization processes to obtain polymers with different monomers at different scales. Based on the products and the key technology accumulation, ChiRial will provide customized materials according to customers' requirements for material performance to meet their diversified needs.

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